This healthy high protein chicken spinach artichoke casserole is loved so much by Mr. Grumbles that I have already made in 3 times in less than 6 weeks! All you need is a large bowl, a mixing spoon and a baking dish - mix everything together, dump it into the baking dish and 30 minutes later, a healthy chicken casserole comes out of the oven!
Chicken Spinach Casserole
I did not grow up eating many casseroles. I have no idea why, but casseroles were just not my Mum's thing. Maybe since she was home during the day, prepping dinner was not as much of a bother as it is for some of us who work full-time away from home.
For Mr. Grumbles and I, casseroles are a lifesaver. Not only are they quick to assemble but I actually think that the leftover casserole sometimes even tastes better the next day. Plus, since there is always some leftover, we can easily pack it for lunch the next day.

High Protein Chicken Casserole
More and more research is pointing to a link between protein intake and anti-aging. What that means is that the more protein we consume, the less we seem to be affected by the aging process.
Protein plays a crucial role in anti-aging by supporting the repair and regeneration of cells, tissues, and muscles. It provides essential amino acids that help maintain skin elasticity, promote collagen production, and reduce the appearance of wrinkles. Adequate protein intake also helps preserve muscle mass, which tends to decline with age, contributing to overall strength, metabolism, and vitality. By supporting these key functions, protein can help slow down visible signs of aging and promote healthier, more resilient skin and body.
This chicken spinach casserole packs in a whopping ???? grams of protein per serving as well as a healthy dose of veggies too!

Why we need more iron
One of the main ingredients in this healthy chicken casserole is spinach. Thanks to Popeye, we all know that spinach contains iron and keeps us nice and strong.
But did you know why else you should be consuming more iron?
- Boosts Energy Levels: Iron is critical for the production of hemoglobin, which carries oxygen to cells. When you're low on iron, your body struggles to produce enough energy, leaving you fatigued.
- Supports Brain Function: Adequate iron levels improve cognitive performance by enhancing oxygen delivery to the brain. This supports focus, memory, and overall mental clarity.
- Enhances Immune System: Iron helps immune cells function properly, making your body more efficient at fighting off infections and healing wounds faster.
- Improves Exercise Performance: Iron-rich blood transports oxygen to muscles more effectively, improving endurance, reducing fatigue, and helping you recover faster after workouts.
- Healthy Hair and Skin: Iron supports the production of collagen and helps deliver nutrients to hair follicles, reducing hair thinning and improving skin health.

Chicken Spinach Artichoke Casserole Substitutions
If you are looking to alter the macros of this recipe or simply don't have some of the ingredients, do not fret! Here are some quick ideas for ingredient swaps as well as to change the macros. Just remember that the nutritional information for this chicken spinach artichoke casserole is for the ingredients listed in the recipe card.
- Cream Cheese - Keep the cream cheese for a keto recipe but swap it out for fat free cream cheese or strained Greek Yogurt. If using yogurt, only use about ½ the amount or the casserole may end up too watery.
- Cottage Cheese - This adds a good amount of protein but you can use sour cream instead if you want to add more fat to the recipe.
- Artichokes - You can use marinated olive oil artichokes for higher fat or omit the artichokes to decrease the carbs in this dish. Omitting the artichokes will remove 10 grams of net carbs from the nutritional content of this recipe.
- Cheese - For a higher keto recipe, use more cheese and decrease the cheese for a lower fat recipe
- Chicken - Use chicken thigh meat for a slight increase in fat. 4 oz of chicken thigh meat will add approximately 9 grams of additional fat.
More Keto Casserole Recipes
- Easy Keto Sausage Stuffed Mushroom Casserole
- Delicious Keto Cheesy Brussels Sprouts Casserole
- The BEST Keto Spinach Gratin Casserole
- Keto Bacon Mushroom Swiss Burger Casserole - Only 7 Ingredients
More High Protein Chicken Recipes
- Super Healthy High Protein Buffalo Chicken Casserole
- The BEST Slow Cooker Keto Chicken Marsala
- High Protein Slow Cooker Sweet Cilantro Chicken - PSMF, Low Carb
Healthy High Protein Chicken Spinach Artichoke Casserole
This healthy high protein chicken spinach artichoke casserole is loved so much by Mr. Grumbles that I have already made in 3 times in less than 6 weeks! All you need is a large bowl, a mixing spoon and a baking dish - mix everything together, dump it into the baking dish and 30 minutes later, a healthy chicken casserole comes out of the oven!
- Total Time: 28 minutes
- Yield: 8 servings 1x
Ingredients
- 113 grams cream cheese, softened
- ½ cup cottage cheese
- ¼ cup mayo
- 1 tsp concentrated chicken broth
- 1 tsp salt
- 1 tsp black pepper
- ¼ tsp cayenne pepper
- 240 g bagged frozen spinach, thawed and squeezed to remove water
- 240 g canned in water artichoke quarters, drained (120 grams once drained)
- 4 oz gouda cheese, shredded
- ¼ cup Parmesan cheese, shredded
- 500 grams chicken breast, raw, boneless, skinless, cut into pieces
Instructions
- Preheat the oven to 400 degrees F. Spray an 8 x 8-inch baking dish with cooking spray and set it to the side.
- In a large bowl, mix together the first 7 ingredients until fully combined. Add the squeeze-dried spinach, drained artichoke hearts and chicken. Stir to combine.
- Add half the shredded gouda cheese and stir once again before spreading the casserole into the dish. Sprinkle the remaining gouda and Parmesan cheese over the top of the casserole.
- Bake for 23-27 minutes or until the top begins to brown and the sides are bubbling.
- Prep Time: 5 minutes
- Cook Time: 23 minutes
- Category: Main Meals
- Method: Baking
- Cuisine: Keto, low carb, high protein
- Diet: Gluten Free
Nutrition
- Serving Size: 1 serving
- Calories: 265
- Sugar: 2
- Fat: 14
- Carbohydrates: 9
- Fiber: 4
- Protein: 25



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